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KMID : 0356919930260010141
Korean Journal of Anesthesiology
1993 Volume.26 No. 1 p.141 ~ p.148
A Comparision of Propofol and Enflurane for Tonsilectomy in Children



Abstract
For anesthesia of sixty children undergoing elective tonsillectomy, we randomly assigned the patients as 2 groups, intravenous propofol induction and 6~12mg/kg/hr propofol infusion with 66% nitrous oxide for maintenance(propofol group) or
intravenous 4
mg/kg thiopental for induction and inhalation of enflurane with 66% nitrous oxide for maintenance(enflurane group).
We compared the effects of two groups for induction time, hemodynamic change, recovery time, and side effects.
@ES The results were as follows.
@EN 1) Time for loss of eyelid reflex was significantly shorter in enflurane group than in propofol group(P<0.05).
2) Heart rate was increased significantly in both groups at l min after intubation, l min after operation, 5 min after end of operation(P<0.05). But there were no significant differences between groups.
3) Systolic and iastolic arterial pressure were increased significantly in both groups at l min after intubation(P<0.05). But there wcre no siginificant differences between groups.
4) The recovery time was shorter siginficantly in propofol group than in enflurane group(P<0.05), and recovery scores according to modified Steward coma scale were higher in propofol group until 25 min after end of anesthesia(P<0.05).
5) Pain on injection at induction was siginificantly more frequent in propofol group than in enflurane group(P<0.05), and excitatory effect during emergence was significantly more frequent in enflurane group than in propofol group(P<0.05).
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